The Best Comprehensive Blood Biomarker Tests (2026 Review)

Who offers the best actionable health insights today? I tested Function Health, Superpower, Oura, Whoop, and Ultrahuman to find out.

For decades, the annual physical has been a black box. You visit a doctor, get a standard lipid panel, and unless you are actively sick, you are told everything is "normal."

But "normal" is not the same as optimal.

We are entering a new era of "Systemic Health," where proactive testing allows you to peek under the hood before symptoms appear. Driven by the longevity movement and popularized by physicians like Dr. Mark Hyman and Dr. Peter Attia, comprehensive blood testing is now accessible without a doctor's referral.

Why this matters: Standard medicine often ignores biomarkers (like ApoB, Lp(a), Homocysteine or Insulin) that predict future disease until it is too late. The companies below don't just test 50-120 biomarkers; they use LLMs (Large Language Models), digital biomarkers (stress, sleep, activity, glucose) and clinician reviews to turn the confusing data into a clear, actionable plan.

Why now: LLMs have commoditized the analysis of complex medical data. What used to require a specialized functional medicine doctor can now be synthesized by smart algorithms and verified by clinicians, making "precision health" accessible to the masses.

I tested the five leading services—Function Health, Superpower, Whoop Advanced Labs, Oura Health Panels, and Ultrahuman Blood Vision—to see which one delivers on the promise of better health.

Quick Summary: The Winners

Best for Deep Medical Insight: Function Health. The current "Gold Standard" for comprehensive blood biomarkers offer a comprehensive panel and a follow up test.
Best Value & Tech-First Experience: Superpower. An affordable entry point ($199) with comprehensive supplement marketplace and interesting AI chat features.
Best for Wearable Owners: Oura & Whoop. Smaller affordable panels that will hopefully be linked to wearable and glucose (Oura) data soon.

Deep Dive: The Reviews

1. Function Health

The Functional Medicine Standard.

The Pitch: Co-founded by Dr. Mark Hyman, Function operates less like a tech startup and more like a high-end functional medicine clinic. It is the only service with Ultrahuman that treats urinalysis (kidney filtration/hydration markers) as a non-negotiable part of the baseline.

The Protocol:

Sample: Blood draw + Urine (Quest Diagnostics)
Frequency: 2x tests per year (Baseline + 6-month follow-up)
Cost: $365/year (Membership includes cost of both tests)

The Science & Experience: Function’s dashboard is dense but medically rigorous. Unlike standard labs that flag only "abnormal" results, Function applies "Optimal" ranges based on longevity literature.

Why it wins: The inclusion of a 6-month follow-up test is critical. It moves the product from "curiosity" to "clinical utility," allowing you to validate if your lifestyle interventions actually worked.
Actionability: If your ApoB is high, you receive a structured nutritional protocol, not just a generic "eat better" nudge.

Verdict: The best choice if you want a complete medical overhaul.

Discount code: Get $25 discount for your test

2. Superpower

The Gamified Health Concierge.

The Pitch: Superpower positions itself as the "OS for your health." While Function feels medical, Superpower feels like a futuristic dashboard. It uses heavy gamification—assigning you a "Superpower Score" and "Biological Age"—to make health optimization addictive.

The Protocol:

Sample: Blood draw (Quest Diagnostics)
Frequency: 1x test per year (Baseline)
Cost: $199/year (Membership + 1 Test included)

The Science & Experience: Superpower’s differentiator is speed and AI. Instead of reading a static PDF, you can chat with your data. You can ask the app, "Why is my Magnesium low?" and get an instant, cited answer.

Note: While they advertise "100+ biomarkers," their baseline panel relies almost exclusively on blood. Urinalysis (for heavy metals/toxins) is an add-on.
The "Bring Your Own Data" Feature: Superpower allows you to upload old PDF lab results. Their AI digitizes them instantly, creating historical trend lines before you even take their test.

Verdict: Best for the "tech-forward" user who wants instant answers via chat and a lower entry price.

Discount code: Get $50 to spend on Superpower platform

3. Whoop Advanced Labs

The Closed-Loop Performance System.

The Pitch: Whoop isn't trying to be your doctor; it’s trying to be your coach. Their "Advanced Labs" (powered by SiPhox or Quest Diagnostics) are designed to explain your wearable data.

The Protocol:

Sample: Blood draw (Quest Diagnostics)
Frequency: Ad-hoc (Pay per test or bundled)
Cost: $99–$199 per pane.

The Science & Experience: Whoop excels at context. It doesn't just measure your Cortisol; it overlays that data against your last 30 days of Sleep and HRV scores.

The Limitation: The panels are smaller (65 markers). You won't get deep thyroid antibodies or heavy metals here.
The Win: If you are a Whoop user, the ability to see why your recovery is tanking (e.g., "Low Ferritin is correlated with your low strain tolerance") is a game changer for training.

Verdict: Essential for endurance athletes who want to correlate recovery with blood data.

Discount code: Get 1 free month of Whoop

4. Oura Health Panels

The Metabolic Monitor.

The Pitch: Oura has recently expanded from sleep tracking into metabolic health. Partnering with Quest Diagnostics, they offer specific "Health Panels" designed to identify the biological drivers of poor sleep and low energy.

The Protocol:

Sample: Blood draw (Quest Diagnostics)
Frequency: Ad-hoc (Pay per panel)
Cost: $99–$149 per panel

The Science & Experience: Oura's panels are generally smaller and more targeted (50 markers) than Function or Superpower. They focus on the basics: Lipid Panel, HbA1c, Iron, and Inflammation.

The Integration: Results appear directly in the Oura app. The app attempts to connect the dots between your biology and your "Readiness" score.
The Cons: Unlike Whoop and Superpower, Oura does not currently offer a robust "Upload PDF" feature for bringing in outside lab results. You are largely limited to analyzing the tests you buy through them.

Verdict: A great "check-engine light." Perfect for spot-checking specific suspicions (e.g., "Is my Vitamin D low?") without committing to a full medical membership.

Discount code: Get 10% off your ring

5. Ultrahuman Blood Vision

The "Cyborg" Health Ecosystem.

The Pitch: Ultrahuman is building the most aggressive "Bio-Convergence" platform. They natively integrate Continuous Glucose Monitor (CGM) data with blood chemistry.

The Protocol:

Sample: Blood draw + Urine (Quest Diagnostics)
Frequency: Annual (Comprehensive plan)
Cost: $499 (Comprehensive "Blood Vision" plan)

The Science & Experience: Ultrahuman uses a feature called "UltraTrace" to correlate biomarkers with glucose spikes.

The "Vision Cloud": This is their killer feature. You can upload any past blood test (from any country/lab) and their AI will visualize it for free.
Metabolic Focus: Because of their CGM roots, their insights on Insulin Resistance and Metabolic flexibility are arguably the most granular of the group.

Verdict: The best choice for "biohackers" who already use their CGM and smart ring.

Discount code: Get the best price (when rings become available in the US)

Head-to-Head: The Comparison Charts

1. Annual Cost Breakdown

Note: Prices are subject to change and often have "Introductory" offers.

Service	Price	Value Note
Superpower	$199	Best Entry Price. Includes 1 comprehensive test. Great for establishing a baseline on a budget.
Function	$365	Best Overall Value. Includes 2 tests (Baseline + Follow-up). The cost per biomarker is the lowest in the industry.
Ultrahuman	$499	Premium Pricing. High cost, but includes deep metabolic analysis and CGM software integration.
Whoop	$99 - $199	Add-on Pricing. Good for spot-checking specific issues (Iron/Vitamin D) but expensive for comprehensive monitoring.
Oura	$99 - $149	Add-on Pricing. Affordable way to check specific systems (Heart/Metabolism) without a subscription fee.

1. Biomarker Coverage & Methodology

Feature	Function Health	Superpower	Ultrahuman	Whoop	Oura
Primary Specimen	Venous Blood + Urine	Venous Blood	Venous Blood + Urine	Venous Blood	Venous Blood
Biomarkers	100+	100+	100+	65	50
Renal/Hydration	✅ Yes (Urinalysis)	⚠️ Add-on only	✅ Yes (Urinalysis)	❌ Blood only	❌ Blood only
Re-Test	✅ Included	❌ Paid Add-on	❌ Paid Add-on	❌ Paid Add-on	❌ Paid Add-on
Best For...	Clinical Validity	UX & Speed	Metabolic/CGM Users	Athletes	Sleep/Energy

My Recommendation

Start with Function Health ($365): It is the only service that enforces the scientific method: Test, Intervene, Re-test. The inclusion of the 6-month follow-up and urinalysis makes it the most medically responsible choice.
Choose Superpower ($199): If you are younger, healthy, and on a budget, this is the perfect entry point. The AI chat feature is genuinely useful for learning about your health.
Stick to Whoop or Oura: If you already have their wearable. Both offer good smaller panels that cover what most people need to know. Whoop/Oura don’t much beyond the data, but I’m sure they will soon incorporate the blood biomarkers with wearable and in case of Oura glucose data.
Choose Ultrahuman ($499): If you are already wearing their ring and a CGM. The data synthesis between glucose and blood markers is unique to their ecosystem.

Next Steps: I am currently analyzing the "Action Plans" provided by each service to see which of them offers the best nutritional/lifestyle advice for my slightly elevated ApoB. I will share the comparisons in the follow up posts.

About the Author

Ari Tulla is the Co-founder and CEO of Elo Health, the smart nutrition company turning food into medicine.

As a pioneer in the personalized health space, Ari launched Elo Health to close the gap between diagnostics and daily action. Elo was among the very first platforms to integrate comprehensive blood biomarker testing directly with customized nutrition—long before the current wave of "executive health" startups emerged. This experience gives him a unique insider’s perspective on the accuracy, logistics, and clinical utility of the testing services reviewed here.

Ari treats his body as a living laboratory, rigorously testing every new protocol, wearable, and diagnostic tool to decode the science of longevity. When he isn’t analyzing health data, you can find him climbing mountains or surfing in Northern California.

Follow Ari on Twitter/X and LinkedIn.