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When taken together, vitamin C could break down vitamin B12 in your digestive tract and reduce absorption [1]. To avoid this interaction, wait 2-3 hours to take vitamin C after your B12 supplement.  

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References

  1. Mayo Foundation for Medical Education and Research. (2023, August 10). Vitamin B-12. Mayo Clinic. https://www.mayoclinic.org/drugs-supplements-vitamin-b12/art-20363663%C2%A0