What does a triglyceride test result of 250 mean? Are there any symptoms associated with this triglyceride level?

A triglyceride level of 250 mg/dL is considered high. High triglycerides can put you at greater risk for heart disease, and can also be a sign of serious conditions including type 2 diabetes, prediabetes, metabolic syndrome, and hypothyroidism [2].

People with high triglycerides typically don’t have any symptoms, however, extremely high levels (>1000 mg/dL) can cause pancreatitis, acute inflammation of the pancreas. Symptoms of pancreatitis include severe stomach pain and tenderness, vomiting, diarrhea, high fever, jaundice, and a high heart rate.

Lowering high triglyceride levels will lower your risk of developing heart disease and other health issues. If you already have heart disease, lowering your triglycerides can reduce your odds of serious complications, like a heart attack or stroke. 

Factors that could contribute to a triglyceride level of 250: 

A variety of factors can affect triglyceride levels including your diet, weight, physical activity level, smoking, and drinking. Some medications and diseases also impact triglyceride levels.

• Diet: Diets that are high in fat, added sugar, and refined carbohydrates can increase triglyceride levels.

• Weight: Having excess fat, particularly around the abdomen, can also increase triglycerides.

• Physical Activity: Being active can help lower triglyceride levels.

• Medications: Certain medicines can raise your triglyceride level including corticosteroids, beta-blockers, thiazide diuretics, antivirals, and estrogen.

• Some medical conditions: Diseases involving the thyroid, liver, or kidney, as well as poorly controlled type 2 diabetes, can change triglyceride levels.

• Smoking: Smoking is associated with high triglycerides.

• Excessive alcohol consumption: Heavy drinking can also contribute to high triglyceride levels. 

What to do if your triglyceride level is 250?

Making changes to your diet and adopting healthier habits can help lower your triglyceride level. When it comes to triglyceride levels, the lower, the better. 

To lower your triglycerides:

• Exercise for 30-60 minutes 5x/week.

• Lose weight by reducing your calorie intake.

• Avoid refined carbs and limit added sugars to <25g/day.

• Limit alcoholic beverages to <1-2 drinks per day.

• Eat healthier fats like those found in nuts, seeds, avocados, olive oil, and salmon.

• Avoid trans fats and limit saturated fat to <10% of total calories.

• Quit smoking.

Medications and supplements used to improve triglyceride results

If diet and lifestyle changes do not lower triglyceride levels enough on their own, some medications and supplements may help.

Medications

• Prescription niacin: Niacin is a B vitamin that, when taken at prescription doses, can lower triglyceride levels and improve HDL (good) cholesterol levels. It works by blocking the enzyme responsible for making cholesterol in the liver.

• Fibrates: Fibrates help lower high triglyceride levels and may also help increase HDL (good) cholesterol. Fibrates work by reducing the liver's production of VLDL (the triglyceride-carrying particle in the blood) and by speeding up the removal of triglycerides from the blood.

• Statins: Statins (including atorvastatin, simvastatin, and rosuvastatin)  may be prescribed if your LDL and total cholesterol levels are also elevated. Statins reduce cholesterol production in your liver and lower blood cholesterol levels. Because they typically need to be taken for life, statins are usually only prescribed if diet and lifestyle changes aren’t enough [3].

Supplements

• Fish oil: The omega-3 fatty acids in fish oil can help lower your triglycerides. Prescription fish oil contains more active fatty acids than many nonprescription supplements but can interfere with blood clotting, so check with a doctor before taking a high-dose supplement.